Botox vs. Dysport vs. Letybo
Which Wrinkle Relaxer Fits You?

Let’s Take A Closer Look At The Differences

At first, a lower price per unit might seem like the most important factor when comparing wrinkle relaxers. But once you find out that units differ between brands, it becomes a bit less simple. It's also important to consider timing, treatment area, and how your face moves.

Botox®, Dysport®, and Letybo® all work by temporarily relaxing certain facial muscles to soften expression lines. There isn't one option that's best for everyone. Each has different approved uses, formulas, and dosing, and your facial anatomy and past experiences help decide which is right for you. At Kucumber Skin Lounge, we offer all three options in Seattle, Bellevue, and Bellingham. Here’s a look at how they compare and what Letybo brings to the choices you may already be familiar with.

What Botox, Dysport, and Letybo Have in Common

All three are prescription products made from botulinum toxin type A, often called neuromodulators or wrinkle relaxers. They work by reducing the nerve signals that tell certain muscles to contract. As those muscles relax, the skin above them creases less. This makes them helpful for dynamic wrinkles, which are lines that show up more when you frown, smile, or raise your eyebrows. The goal is often to soften these lines while keeping some natural expression, depending on the area, dose, and your preferences. Deep creases may still be visible even after treatment, and switching brands may not fix that.

The Treatment Area Can Change the Treatment

All three are approved to treat frown lines, which are the vertical “11s” between your eyebrows. If this is your main concern, any of them could be an option after a medical assessment. Your injector should explain why a certain product and dose are right for your facial movement, instead of just focusing on the brand name. Botox Cosmetic is approved for more treatment areas, like crow’s feet, forehead lines, and neck bands. Dysport and Letybo have fewer approved uses in the U.S. If you see them recommended for other facial areas, that’s considered off-label, even if it’s common to see online.

You can find more details about Botox, Dysport, and Letybo on our site. During your consultation, ask which option is being recommended for your concern and what results and risks you can expect for that area.

What Is Letybo, and Where Does It Fit?

Letybo is made by Hugel in South Korea and was approved by the U.S. FDA in 2024. At Kucumber, it’s included in our K-TOX offerings. While some people call it “Korean Botox,” Letybo and Botox are different prescription products, each with its own active ingredients and dosing units. Because it was approved more recently in the U.S., Letybo gives you another option for treating frown lines. However, this doesn’t mean it lasts longer, looks more natural, or is safer than Botox or Dysport. If you’re happy with your current treatment, there’s no automatic reason to switch to a newer brand.

Does a Different Formulation Mean Better Results?

There are real differences in how these products are made, but claims about “purity” or extra proteins need to be understood in context. These details alone don’t show which treatment will look most natural or last the longest. Product labels also warn that comparing antibody formation from different studies can be misleading. A lower percentage doesn’t prove that one brand prevents resistance.

Which Works Faster, and Which Lasts Longer?

All three products can start working within a few days. According to the manufacturer, Botox Cosmetic may show early changes in 24 to 48 hours, while Dysport and Letybo may show improvement in 1 to 3 days. These numbers come from different studies, so they don’t guarantee that one will work faster for you.

Early softening isn’t the final result. You can expect changes to continue over the next few weeks. Botox Cosmetic’s manufacturer says full results appear at 30 days. Your injector can tell you when to check your results and if you need a follow-up. If you have an important event, give yourself time for results to develop and for any bruising to heal, rather than scheduling based on the earliest possible onset.

For maintenance, plan on results lasting about three to four months, though this can vary by product, dose, treatment area, and your individual response. Dysport’s manufacturer reports results lasting up to five months in some studies, and Letybo’s up to four months. Since these studies measure improvement differently, the longest results don’t always predict which treatment will last longest for you.

If you’ve had wrinkle relaxer treatments before, bring details like the date, brand, areas treated, and any dose information you have. Knowing when your movement returned and whether you liked the results helps your injector more than just comparing brands.

Compare the Total Treatment Cost, Not Just Unit Prices

A unit is a way to measure a product’s biological activity, but each brand uses its own testing method. It’s not like a milliliter, which is the same everywhere. Botox, Dysport, and Letybo units aren’t interchangeable, so a lower unit price doesn’t always mean a lower total cost. For example, the recommended frown-line doses are 20 units for Botox Cosmetic, 50 units for Dysport, and 20 units for Letybo. These numbers are specific to each product and aren’t meant to be converted or used as personal dosing advice. A higher number of Dysport units doesn’t mean the treatment is stronger.

At Kucumber, Botox pricing is based on units, and your quote will depend on your treatment plan. To compare options, ask for the total price for your specific concern, the recommended product and dose, and what’s included in follow-up. Be sure to check current offers and eligibility before treatment. No brand is always the cheapest for everyone.

What Helps Results Look Natural?

Getting natural-looking results depends on both the treatment plan and the product. At Kucumber, we talk with you about your goals and observe how your facial muscles move before making a recommendation. This helps us match the lines you want to soften with the muscles causing them.

Be clear about what you want. For example, you might prefer less movement between your brows but want to keep your forehead expressive. Your injector will also look at things like asymmetry, muscle strength, and the position of your brows or eyelids. Stronger facial muscles can affect dosing, but that doesn’t mean one brand is always better. Terms like “more precise,” “softer,” or “more spreadable” can make treatments sound simpler than they are. Ask your provider how the placement and dose will help you reach your goals, and what kind of movement you can expect afterward.

Safety and Downtime: What All Three Require

Most people can get back to their usual activities right away, but you might notice small injection marks, soreness, swelling, bruising, or a headache. Sometimes, nearby muscles can become weak, which may cause a drooping brow or eyelid. Be sure to follow your aftercare instructions, including advice about touching the area and exercise. All botulinum toxin products carry a boxed warning about effects spreading beyond the injection site. Seek immediate medical attention for trouble breathing, swallowing, or speaking, or generalized muscle weakness after treatment. These symptoms can occur hours to weeks after injections.

Before your treatment, let your provider know about any past reactions to botulinum toxin, injection-site infections, muscle or nerve conditions, swallowing or breathing problems, and all medications or supplements you take. Dysport shouldn’t be used if you have a cow’s milk protein allergy, which is not the same as lactose intolerance. If you are pregnant or breastfeeding, talk with your provider, as elective treatment is usually postponed.

A Few More Questions About Choosing a Wrinkle Relaxer

Can I switch from Botox or Dysport to Letybo?

Switching might be possible after your injector looks at your response and treatment history. Be sure to share the exact product and date of your last injections, even if you had them somewhere else. Your provider should plan the timing and dose for the new product, not just match the unit numbers.

Is one better for first-time patients?

There’s no one best product for first-time patients. The area you want treated, your health history, facial movement, and how much softening you want all help guide the choice. Ask your injector to explain their plan and how they’ll check your results before you decide.

Do wrinkle relaxers replace dermal fillers?

No, wrinkle relaxers don’t replace dermal fillers. Wrinkle relaxers work by reducing muscle activity, while fillers add volume or support in certain areas. If a crease is due to volume loss or stays even when your face is at rest, you might need a different treatment. Your consultation should help figure out what’s causing the concern before choosing an injectable.

Find Your Fit at Kucumber Skin Lounge

You’re welcome to come to your consultation with a preference or with questions about all three options. At Kucumber Skin Lounge in Seattle, Bellevue, and Bellingham, we’ll talk about your concerns, treatment history, and which options fit your goals. Bring any details from past injections so we can discuss what you’d like to keep or change.

Book a free consultation to explore your options with our team.